BDBM50319656 2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-2-phenylacetamide::CHEMBL1084108

SMILES: Clc1cc2c(cc[nH]c2=O)cc1NC(=O)C(NCc1ccccc1)c1ccccc1

InChI Key: InChIKey=QJDSLVQBWYNFIQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319656   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50319656 (2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...) Show SMILES Clc1cc2c(cc[nH]c2=O)cc1NC(=O)C(NCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H20ClN3O2/c25-20-14-19-18(11-12-26-23(19)29)13-21(20)28-24(30)22(17-9-5-2-6-10-17)27-15-16-7-3-1-4-8-16/h1-14,22,27H,15H2,(H,26,29)(H,28,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 20: 3235-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.070 BindingDB Entry DOI: 10.7270/Q21N819Z
					More data for this Ligand-Target Pair