BDBM50319835 1-(2-(2-cyclopropoxyphenyl)-1-phenylethyl)piperazine::CHEMBL1083705

SMILES: C(C(N1CCNCC1)c1ccccc1)c1ccccc1OC1CC1

InChI Key: InChIKey=NSVJPFSJIISEIG-UHFFFAOYSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50319835 (1-(2-(2-cyclopropoxyphenyl)-1-phenylethyl)piperazi...) Show SMILES C(C(N1CCNCC1)c1ccccc1)c1ccccc1OC1CC1 Show InChI InChI=1S/C21H26N2O/c1-2-6-17(7-3-1)20(23-14-12-22-13-15-23)16-18-8-4-5-9-21(18)24-19-10-11-19/h1-9,19-20,22H,10-16H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 3788-92 (2010) Article DOI: 10.1016/j.bmcl.2010.04.052 BindingDB Entry DOI: 10.7270/Q2SN09X4
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50319835 (1-(2-(2-cyclopropoxyphenyl)-1-phenylethyl)piperazi...) Show SMILES C(C(N1CCNCC1)c1ccccc1)c1ccccc1OC1CC1 Show InChI InChI=1S/C21H26N2O/c1-2-6-17(7-3-1)20(23-14-12-22-13-15-23)16-18-8-4-5-9-21(18)24-19-10-11-19/h1-9,19-20,22H,10-16H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 3788-92 (2010) Article DOI: 10.1016/j.bmcl.2010.04.052 BindingDB Entry DOI: 10.7270/Q2SN09X4
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50319835 (1-(2-(2-cyclopropoxyphenyl)-1-phenylethyl)piperazi...) Show SMILES C(C(N1CCNCC1)c1ccccc1)c1ccccc1OC1CC1 Show InChI InChI=1S/C21H26N2O/c1-2-6-17(7-3-1)20(23-14-12-22-13-15-23)16-18-8-4-5-9-21(18)24-19-10-11-19/h1-9,19-20,22H,10-16H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 3788-92 (2010) Article DOI: 10.1016/j.bmcl.2010.04.052 BindingDB Entry DOI: 10.7270/Q2SN09X4
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50319835 (1-(2-(2-cyclopropoxyphenyl)-1-phenylethyl)piperazi...) Show SMILES C(C(N1CCNCC1)c1ccccc1)c1ccccc1OC1CC1 Show InChI InChI=1S/C21H26N2O/c1-2-6-17(7-3-1)20(23-14-12-22-13-15-23)16-18-8-4-5-9-21(18)24-19-10-11-19/h1-9,19-20,22H,10-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG				Bioorg Med Chem Lett 20: 3788-92 (2010) Article DOI: 10.1016/j.bmcl.2010.04.052 BindingDB Entry DOI: 10.7270/Q2SN09X4
					More data for this Ligand-Target Pair