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SMILES: CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COC(C1CCC1)c1ccccc1

InChI Key: InChIKey=HWIDACPLMPKIBW-AVJYQCBHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320012   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50320012
PNG
((2R)-1-(cyclobutyl(phenyl)methoxy)-3-(2-methyl-1-(...)
Show SMILES CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COC(C1CCC1)c1ccccc1 |r|
Show InChI InChI=1S/C28H35NO2/c1-28(2,18-21-15-16-22-9-6-7-12-25(22)17-21)29-19-26(30)20-31-27(24-13-8-14-24)23-10-4-3-5-11-23/h3-7,9-12,15-17,24,26-27,29-30H,8,13-14,18-20H2,1-2H3/t26-,27?/m1/s1
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Article
PubMed
n/an/a 74n/an/an/an/an/an/a



Central Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assay

Bioorg Med Chem Lett 20: 3809-13 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.035
BindingDB Entry DOI: 10.7270/Q2765FGD
More data for this
Ligand-Target Pair