BDBM50320734 4-Hydroxy-benzoic acid hydrazide::4-hydroxybenzohydrazide::CHEMBL124267

SMILES: NNC(=O)c1ccc(O)cc1

InChI Key: InChIKey=ZMZGIVVRBMFZSG-UHFFFAOYSA-N

Data: 2 KI  2 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin B (Capra hircus (Goat))	BDBM50320734 (4-Hydroxy-benzoic acid hydrazide | 4-hydroxybenzoh...) Show SMILES NNC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C7H8N2O2/c8-9-7(11)5-1-3-6(10)4-2-5/h1-4,10H,8H2,(H,9,11)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Competitive inhibition of cathepsin B in goat liver using alpha-N-benzoyl-D,L-arginine-2-naphthylamide as substrate by colorimetric analysis				Eur J Med Chem 77: 231-42 (2014) Article DOI: 10.1016/j.ejmech.2014.03.007 BindingDB Entry DOI: 10.7270/Q2319XDV
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50320734 (4-Hydroxy-benzoic acid hydrazide | 4-hydroxybenzoh...) Show SMILES NNC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C7H8N2O2/c8-9-7(11)5-1-3-6(10)4-2-5/h1-4,10H,8H2,(H,9,11)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.77E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of mashroom tyrosinase				Bioorg Med Chem 18: 4042-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.021 BindingDB Entry DOI: 10.7270/Q2FJ2GZ8
					More data for this Ligand-Target Pair
Myeloperoxidase (Homo sapiens (Human))	BDBM50320734 (4-Hydroxy-benzoic acid hydrazide | 4-hydroxybenzoh...) Show SMILES NNC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C7H8N2O2/c8-9-7(11)5-1-3-6(10)4-2-5/h1-4,10H,8H2,(H,9,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Sarajevo School of Science and Technology Curated by ChEMBL					Assay Description Inhibition of MPO in human neutrophils using H2O2 as substrate measured after 5 mins				Bioorg Med Chem Lett 29: 1-7 (2019) Article DOI: 10.1016/j.bmcl.2018.11.031
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM50320734 (4-Hydroxy-benzoic acid hydrazide | 4-hydroxybenzoh...) Show SMILES NNC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C7H8N2O2/c8-9-7(11)5-1-3-6(10)4-2-5/h1-4,10H,8H2,(H,9,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of KDM5A (unknown origin) using substrate peptide/ascorbate/2-OG/ Fe(2) as substrate preincubated for 15 mins followed by addition of subs...				Bioorg Med Chem Lett 26: 2284-8 (2016) BindingDB Entry DOI: 10.7270/Q2XP76TS
					More data for this Ligand-Target Pair