BDBM50320885 5-Bipheny-4-ylmethylene-3-(3-chloro-benzyl)-thiazolidine-2,4-dione::CHEMBL1165451

SMILES: Clc1cccc(CN2C(=O)S\C(=C/c3ccc(cc3)-c3ccccc3)C2=O)c1

InChI Key: InChIKey=KNTRBWZBLRDYCS-STZFKDTASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50320885 (5-Bipheny-4-ylmethylene-3-(3-chloro-benzyl)-thiazo...) Show SMILES Clc1cccc(CN2C(=O)S\C(=C/c3ccc(cc3)-c3ccccc3)C2=O)c1 Show InChI InChI=1S/C23H16ClNO2S/c24-20-8-4-5-17(13-20)15-25-22(26)21(28-23(25)27)14-16-9-11-19(12-10-16)18-6-2-1-3-7-18/h1-14H,15H2/b21-14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.36E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Pernambuco Curated by ChEMBL					Assay Description Displacement of [3H]rosiglitazone from human PPARgamma ligand binding domain expressed in Escherichia coli BL21 after 12 hrs by liquid scintillation ...				Bioorg Med Chem 18: 3805-11 (2010) Article DOI: 10.1016/j.bmc.2010.04.045 BindingDB Entry DOI: 10.7270/Q28S4Q24
					More data for this Ligand-Target Pair