BDBM50321377 2-(3-(4-chlorophenylthio)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)aceticacid::CHEMBL1171955

SMILES: OC(=O)CN1c2ccccc2CCC(Sc2ccc(Cl)cc2)C1=O

InChI Key: InChIKey=HCEJWCRNRFAUCM-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321377   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide dependent protein kinase-1 (Homo sapiens (Human))	BDBM50321377 (2-(3-(4-chlorophenylthio)-2-oxo-2,3,4,5-tetrahydro...) Show SMILES OC(=O)CN1c2ccccc2CCC(Sc2ccc(Cl)cc2)C1=O Show InChI InChI=1S/C18H16ClNO3S/c19-13-6-8-14(9-7-13)24-16-10-5-12-3-1-2-4-15(12)20(18(16)23)11-17(21)22/h1-4,6-9,16H,5,10-11H2,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Displacement of PIFtide from His-tagged PDK1 by HTRF assay				Bioorg Med Chem Lett 20: 3897-902 (2010) Article DOI: 10.1016/j.bmcl.2010.05.019 BindingDB Entry DOI: 10.7270/Q2Z60Q1H
					More data for this Ligand-Target Pair