Found 7 hits for monomerid = 50321446 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cyclin-Dependent Kinase 7 (CDK7)
(Homo sapiens (Human)) | BDBM50321446
(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)Show InChI InChI=1S/C14H12F3NO2S/c1-10-5-7-13(8-6-10)21(19,20)18-12-4-2-3-11(9-12)14(15,16)17/h2-9,18H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of human CDK7/Cyclin H/MAT1 |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
CDK6/cyclin D1
(Homo sapiens (Human)) | BDBM50321446
(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)Show InChI InChI=1S/C14H12F3NO2S/c1-10-5-7-13(8-6-10)21(19,20)18-12-4-2-3-11(9-12)14(15,16)17/h2-9,18H,1H3 | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.09E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of human CDK6/Cyclin D1 |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
Cyclin-Dependent Kinase 1 (CDK1)
(Homo sapiens (Human)) | BDBM50321446
(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)Show InChI InChI=1S/C14H12F3NO2S/c1-10-5-7-13(8-6-10)21(19,20)18-12-4-2-3-11(9-12)14(15,16)17/h2-9,18H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of human CDK1/cyclin B |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
Free fatty acid receptor 1
(Homo sapiens (Human)) | BDBM50321446
(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)Show InChI InChI=1S/C14H12F3NO2S/c1-10-5-7-13(8-6-10)21(19,20)18-12-4-2-3-11(9-12)14(15,16)17/h2-9,18H,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| | n/a | n/a | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Protein kinase Pfmrk
(Plasmodium falciparum) | BDBM50321446
(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)Show InChI InChI=1S/C14H12F3NO2S/c1-10-5-7-13(8-6-10)21(19,20)18-12-4-2-3-11(9-12)14(15,16)17/h2-9,18H,1H3 | UniProtKB/TrEMBL
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation counting |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
Free fatty acid receptor 4
(Homo sapiens) | BDBM50321446
(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)Show InChI InChI=1S/C14H12F3NO2S/c1-10-5-7-13(8-6-10)21(19,20)18-12-4-2-3-11(9-12)14(15,16)17/h2-9,18H,1H3 | GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| | n/a | n/a | n/a | n/a | 2.95E+4 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
CDK2/Cyclin A/Cyclin A1
(Homo sapiens (Human)) | BDBM50321446
(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)Show InChI InChI=1S/C14H12F3NO2S/c1-10-5-7-13(8-6-10)21(19,20)18-12-4-2-3-11(9-12)14(15,16)17/h2-9,18H,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of human CDK2/Cyclin A |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |