Found 5 hits for monomerid = 50321447 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cyclin-H/Cyclin-dependent kinase 7
(Homo sapiens (Human)) | BDBM50321447
(2,4,5-trichloro-N-(3-(trifluoromethyl)phenyl)benze...)Show SMILES FC(F)(F)c1cccc(NS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)c1 Show InChI InChI=1S/C13H7Cl3F3NO2S/c14-9-5-11(16)12(6-10(9)15)23(21,22)20-8-3-1-2-7(4-8)13(17,18)19/h1-6,20H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of human CDK7/Cyclin H/MAT1 |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 6/G1/S-specific cyclin-D1
(Homo sapiens (Human)) | BDBM50321447
(2,4,5-trichloro-N-(3-(trifluoromethyl)phenyl)benze...)Show SMILES FC(F)(F)c1cccc(NS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)c1 Show InChI InChI=1S/C13H7Cl3F3NO2S/c14-9-5-11(16)12(6-10(9)15)23(21,22)20-8-3-1-2-7(4-8)13(17,18)19/h1-6,20H | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of human CDK6/Cyclin D1 |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
MO15-related protein kinase Pfmrk
(Plasmodium falciparum) | BDBM50321447
(2,4,5-trichloro-N-(3-(trifluoromethyl)phenyl)benze...)Show SMILES FC(F)(F)c1cccc(NS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)c1 Show InChI InChI=1S/C13H7Cl3F3NO2S/c14-9-5-11(16)12(6-10(9)15)23(21,22)20-8-3-1-2-7(4-8)13(17,18)19/h1-6,20H | UniProtKB/TrEMBL
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation counting |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50321447
(2,4,5-trichloro-N-(3-(trifluoromethyl)phenyl)benze...)Show SMILES FC(F)(F)c1cccc(NS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)c1 Show InChI InChI=1S/C13H7Cl3F3NO2S/c14-9-5-11(16)12(6-10(9)15)23(21,22)20-8-3-1-2-7(4-8)13(17,18)19/h1-6,20H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of human CDK2/Cyclin A |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1
(Homo sapiens (Human)) | BDBM50321447
(2,4,5-trichloro-N-(3-(trifluoromethyl)phenyl)benze...)Show SMILES FC(F)(F)c1cccc(NS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)c1 Show InChI InChI=1S/C13H7Cl3F3NO2S/c14-9-5-11(16)12(6-10(9)15)23(21,22)20-8-3-1-2-7(4-8)13(17,18)19/h1-6,20H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of human CDK1/cyclin B |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |