Found 9 hits for monomerid = 50321461 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
CDK2/Cyclin A/Cyclin A1
(Homo sapiens (Human)) | BDBM50321461
(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)Show SMILES Clc1cc(c(Cl)s1)S(=O)(=O)N(C(=O)CBr)c1ccccc1 Show InChI InChI=1S/C12H8BrCl2NO3S2/c13-7-11(17)16(8-4-2-1-3-5-8)21(18,19)9-6-10(14)20-12(9)15/h1-6H,7H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of human CDK2/Cyclin A |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
Cyclin-Dependent Kinase 1 (CDK1)
(Homo sapiens (Human)) | BDBM50321461
(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)Show SMILES Clc1cc(c(Cl)s1)S(=O)(=O)N(C(=O)CBr)c1ccccc1 Show InChI InChI=1S/C12H8BrCl2NO3S2/c13-7-11(17)16(8-4-2-1-3-5-8)21(18,19)9-6-10(14)20-12(9)15/h1-6H,7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of human CDK1/cyclin B |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
Cyclin-Dependent Kinase 7 (CDK7)
(Homo sapiens (Human)) | BDBM50321461
(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)Show SMILES Clc1cc(c(Cl)s1)S(=O)(=O)N(C(=O)CBr)c1ccccc1 Show InChI InChI=1S/C12H8BrCl2NO3S2/c13-7-11(17)16(8-4-2-1-3-5-8)21(18,19)9-6-10(14)20-12(9)15/h1-6H,7H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of human CDK7/Cyclin H/MAT1 |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
CDK6/cyclin D1
(Homo sapiens (Human)) | BDBM50321461
(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)Show SMILES Clc1cc(c(Cl)s1)S(=O)(=O)N(C(=O)CBr)c1ccccc1 Show InChI InChI=1S/C12H8BrCl2NO3S2/c13-7-11(17)16(8-4-2-1-3-5-8)21(18,19)9-6-10(14)20-12(9)15/h1-6H,7H2 | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.49E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of human CDK6/Cyclin D1 |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
Protein kinase Pfmrk
(Plasmodium falciparum) | BDBM50321461
(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)Show SMILES Clc1cc(c(Cl)s1)S(=O)(=O)N(C(=O)CBr)c1ccccc1 Show InChI InChI=1S/C12H8BrCl2NO3S2/c13-7-11(17)16(8-4-2-1-3-5-8)21(18,19)9-6-10(14)20-12(9)15/h1-6H,7H2 | UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Walter Reed Army Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation counting |
Bioorg Med Chem Lett 20: 3863-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.039 BindingDB Entry DOI: 10.7270/Q2F47Q3Q |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 7
(Homo sapiens (Human)) | BDBM50321461
(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)Show SMILES Clc1cc(c(Cl)s1)S(=O)(=O)N(C(=O)CBr)c1ccccc1 Show InChI InChI=1S/C12H8BrCl2NO3S2/c13-7-11(17)16(8-4-2-1-3-5-8)21(18,19)9-6-10(14)20-12(9)15/h1-6H,7H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Montclair State University
Curated by ChEMBL
| Assay Description Inhibition of human CDK7 |
Bioorg Med Chem Lett 22: 6788-93 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.044 BindingDB Entry DOI: 10.7270/Q26H4JJZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 6
(Homo sapiens (Human)) | BDBM50321461
(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)Show SMILES Clc1cc(c(Cl)s1)S(=O)(=O)N(C(=O)CBr)c1ccccc1 Show InChI InChI=1S/C12H8BrCl2NO3S2/c13-7-11(17)16(8-4-2-1-3-5-8)21(18,19)9-6-10(14)20-12(9)15/h1-6H,7H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Montclair State University
Curated by ChEMBL
| Assay Description Inhibition of human CDK6 |
Bioorg Med Chem Lett 22: 6788-93 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.044 BindingDB Entry DOI: 10.7270/Q26H4JJZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50321461
(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)Show SMILES Clc1cc(c(Cl)s1)S(=O)(=O)N(C(=O)CBr)c1ccccc1 Show InChI InChI=1S/C12H8BrCl2NO3S2/c13-7-11(17)16(8-4-2-1-3-5-8)21(18,19)9-6-10(14)20-12(9)15/h1-6H,7H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Montclair State University
Curated by ChEMBL
| Assay Description Inhibition of human CDK2 |
Bioorg Med Chem Lett 22: 6788-93 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.044 BindingDB Entry DOI: 10.7270/Q26H4JJZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50321461
(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)Show SMILES Clc1cc(c(Cl)s1)S(=O)(=O)N(C(=O)CBr)c1ccccc1 Show InChI InChI=1S/C12H8BrCl2NO3S2/c13-7-11(17)16(8-4-2-1-3-5-8)21(18,19)9-6-10(14)20-12(9)15/h1-6H,7H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Montclair State University
Curated by ChEMBL
| Assay Description Inhibition of human CDK1 |
Bioorg Med Chem Lett 22: 6788-93 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.044 BindingDB Entry DOI: 10.7270/Q26H4JJZ |
More data for this Ligand-Target Pair | |