BDBM50321507 (4-cyclopropyl-1,4-diazepan-1-yl)(6-phenoxypyridin-3-yl)methanone::CHEMBL1171757

SMILES: O=C(N1CCCN(CC1)C1CC1)c1ccc(Oc2ccccc2)nc1

InChI Key: InChIKey=HDCILHQMVLSSKP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321507   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321507 ((4-cyclopropyl-1,4-diazepan-1-yl)(6-phenoxypyridin...) Show SMILES O=C(N1CCCN(CC1)C1CC1)c1ccc(Oc2ccccc2)nc1 Show InChI InChI=1S/C20H23N3O2/c24-20(23-12-4-11-22(13-14-23)17-8-9-17)16-7-10-19(21-15-16)25-18-5-2-1-3-6-18/h1-3,5-7,10,15,17H,4,8-9,11-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]-iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by scintillation countin...				Bioorg Med Chem Lett 20: 4210-4 (2010) Article DOI: 10.1016/j.bmcl.2010.05.041 BindingDB Entry DOI: 10.7270/Q29G5NS9
					More data for this Ligand-Target Pair