BDBM50321754 (R)-(1-benzyl-6'-methoxy-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran]-2'-yl)methanol::CHEMBL1170965

SMILES: CO[C@H]1Cc2sc(CO)cc2C2(CCN(Cc3ccccc3)CC2)O1

InChI Key: InChIKey=AQFKRSCFWQXDAD-LJQANCHMSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321754   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50321754 ((R)-(1-benzyl-6'-methoxy-6',7'-dihydrospiro[piperi...) Show SMILES CO[C@H]1Cc2sc(CO)cc2C2(CCN(Cc3ccccc3)CC2)O1 |r| Show InChI InChI=1S/C20H25NO3S/c1-23-19-12-18-17(11-16(14-22)25-18)20(24-19)7-9-21(10-8-20)13-15-5-3-2-4-6-15/h2-6,11,19,22H,7-10,12-14H2,1H3/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Eur J Med Chem 45: 3116-24 (2010) Article DOI: 10.1016/j.ejmech.2010.03.048 BindingDB Entry DOI: 10.7270/Q2XD11V4
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50321754 ((R)-(1-benzyl-6'-methoxy-6',7'-dihydrospiro[piperi...) Show SMILES CO[C@H]1Cc2sc(CO)cc2C2(CCN(Cc3ccccc3)CC2)O1 |r| Show InChI InChI=1S/C20H25NO3S/c1-23-19-12-18-17(11-16(14-22)25-18)20(24-19)7-9-21(10-8-20)13-15-5-3-2-4-6-15/h2-6,11,19,22H,7-10,12-14H2,1H3/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)pentazocine from guinea pig brain sigma 1-type opioid receptor after 120 mins by scintillation counting analysis				J Med Chem 55: 5350-60 (2012) Article DOI: 10.1021/jm300302p BindingDB Entry DOI: 10.7270/Q2VX0HMZ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50321754 ((R)-(1-benzyl-6'-methoxy-6',7'-dihydrospiro[piperi...) Show SMILES CO[C@H]1Cc2sc(CO)cc2C2(CCN(Cc3ccccc3)CC2)O1 |r| Show InChI InChI=1S/C20H25NO3S/c1-23-19-12-18-17(11-16(14-22)25-18)20(24-19)7-9-21(10-8-20)13-15-5-3-2-4-6-15/h2-6,11,19,22H,7-10,12-14H2,1H3/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Eur J Med Chem 45: 3116-24 (2010) Article DOI: 10.1016/j.ejmech.2010.03.048 BindingDB Entry DOI: 10.7270/Q2XD11V4
					More data for this Ligand-Target Pair