BDBM50321792 1'-methyl-1-(3-phenylpropyl)-6',7'-dihydro-1'H-spiro[piperidine-4,4'-pyrano[4,3-c]pyrazole]::CHEMBL1170545

SMILES: Cn1ncc2c1CCOC21CCN(CCCc2ccccc2)CC1

InChI Key: InChIKey=WUCUMYRTPVDQAQ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321792   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50321792 (1'-methyl-1-(3-phenylpropyl)-6',7'-dihydro-1'H-spi...) Show SMILES Cn1ncc2c1CCOC21CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C20H27N3O/c1-22-19-9-15-24-20(18(19)16-21-22)10-13-23(14-11-20)12-5-8-17-6-3-2-4-7-17/h2-4,6-7,16H,5,8-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Eur J Med Chem 45: 3116-24 (2010) Article DOI: 10.1016/j.ejmech.2010.03.048 BindingDB Entry DOI: 10.7270/Q2XD11V4
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50321792 (1'-methyl-1-(3-phenylpropyl)-6',7'-dihydro-1'H-spi...) Show SMILES Cn1ncc2c1CCOC21CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C20H27N3O/c1-22-19-9-15-24-20(18(19)16-21-22)10-13-23(14-11-20)12-5-8-17-6-3-2-4-7-17/h2-4,6-7,16H,5,8-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of (+)-[3H]pentazocine from guinea pig brain sigma 1 receptor after 180 mins by scintillation counting				J Med Chem 54: 6704-13 (2011) Article DOI: 10.1021/jm200585k BindingDB Entry DOI: 10.7270/Q22R3SN0
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50321792 (1'-methyl-1-(3-phenylpropyl)-6',7'-dihydro-1'H-spi...) Show SMILES Cn1ncc2c1CCOC21CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C20H27N3O/c1-22-19-9-15-24-20(18(19)16-21-22)10-13-23(14-11-20)12-5-8-17-6-3-2-4-7-17/h2-4,6-7,16H,5,8-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Eur J Med Chem 45: 3116-24 (2010) Article DOI: 10.1016/j.ejmech.2010.03.048 BindingDB Entry DOI: 10.7270/Q2XD11V4
					More data for this Ligand-Target Pair