BDBM50321807 (R)-1-benzyl-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran]-6'-carboxamide::CHEMBL1169739

SMILES: NC(=O)[C@H]1Cc2sccc2C2(CCN(Cc3ccccc3)CC2)O1

InChI Key: InChIKey=UGWBPJCGWLMJQZ-MRXNPFEDSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50321807 ((R)-1-benzyl-6',7'-dihydrospiro[piperidine-4,4'-th...) Show SMILES NC(=O)[C@H]1Cc2sccc2C2(CCN(Cc3ccccc3)CC2)O1 |r| Show InChI InChI=1S/C19H22N2O2S/c20-18(22)16-12-17-15(6-11-24-17)19(23-16)7-9-21(10-8-19)13-14-4-2-1-3-5-14/h1-6,11,16H,7-10,12-13H2,(H2,20,22)/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)pentazocine from guinea pig brain sigma 1-type opioid receptor after 120 mins by scintillation counting analysis				J Med Chem 55: 5350-60 (2012) Article DOI: 10.1021/jm300302p BindingDB Entry DOI: 10.7270/Q2VX0HMZ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50321807 ((R)-1-benzyl-6',7'-dihydrospiro[piperidine-4,4'-th...) Show SMILES NC(=O)[C@H]1Cc2sccc2C2(CCN(Cc3ccccc3)CC2)O1 |r| Show InChI InChI=1S/C19H22N2O2S/c20-18(22)16-12-17-15(6-11-24-17)19(23-16)7-9-21(10-8-19)13-14-4-2-1-3-5-14/h1-6,11,16H,7-10,12-13H2,(H2,20,22)/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Eur J Med Chem 45: 3116-24 (2010) Article DOI: 10.1016/j.ejmech.2010.03.048 BindingDB Entry DOI: 10.7270/Q2XD11V4
					More data for this Ligand-Target Pair