BDBM50321814 4-((1H-Imidazol-4-yl)methyl)-1-(biphenyl-4-yl)piperidine::CHEMBL1173391

SMILES: C(C1CCN(CC1)c1ccc(cc1)-c1ccccc1)c1cnc[nH]1

InChI Key: InChIKey=YQSXEBUURNJWNA-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321814 (4-((1H-Imidazol-4-yl)methyl)-1-(biphenyl-4-yl)pipe...) Show SMILES C(C1CCN(CC1)c1ccc(cc1)-c1ccccc1)c1cnc[nH]1 Show InChI InChI=1S/C21H23N3/c1-2-4-18(5-3-1)19-6-8-21(9-7-19)24-12-10-17(11-13-24)14-20-15-22-16-23-20/h1-9,15-17H,10-14H2,(H,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321814 (4-((1H-Imidazol-4-yl)methyl)-1-(biphenyl-4-yl)pipe...) Show SMILES C(C1CCN(CC1)c1ccc(cc1)-c1ccccc1)c1cnc[nH]1 Show InChI InChI=1S/C21H23N3/c1-2-4-18(5-3-1)19-6-8-21(9-7-19)24-12-10-17(11-13-24)14-20-15-22-16-23-20/h1-9,15-17H,10-14H2,(H,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	347	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of RAHM-induced [35S]GTPgammaS bindin...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair