BDBM50321816 4-((1H-Imidazol-4-yl)methyl)-1-(4-methoxyphenyl)piperidine::CHEMBL1172775

SMILES: COc1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1

InChI Key: InChIKey=XGWXPMUNGMSGIF-UHFFFAOYSA-N

Data: 4 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50321816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321816 (4-((1H-Imidazol-4-yl)methyl)-1-(4-methoxyphenyl)pi...) Show SMILES COc1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C16H21N3O/c1-20-16-4-2-15(3-5-16)19-8-6-13(7-9-19)10-14-11-17-12-18-14/h2-5,11-13H,6-10H2,1H3,(H,17,18)	Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50321816 (4-((1H-Imidazol-4-yl)methyl)-1-(4-methoxyphenyl)pi...) Show SMILES COc1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C16H21N3O/c1-20-16-4-2-15(3-5-16)19-8-6-13(7-9-19)10-14-11-17-12-18-14/h2-5,11-13H,6-10H2,1H3,(H,17,18)	PDB Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H]rilamine from human histamine H1 receptor expressed in CHO cells after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H2 Receptor (Homo sapiens (Human))	BDBM50321816 (4-((1H-Imidazol-4-yl)methyl)-1-(4-methoxyphenyl)pi...) Show SMILES COc1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C16H21N3O/c1-20-16-4-2-15(3-5-16)19-8-6-13(7-9-19)10-14-11-17-12-18-14/h2-5,11-13H,6-10H2,1H3,(H,17,18)	Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [125I]aminopotentidine from human histamine H2 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50321816 (4-((1H-Imidazol-4-yl)methyl)-1-(4-methoxyphenyl)pi...) Show SMILES COc1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C16H21N3O/c1-20-16-4-2-15(3-5-16)19-8-6-13(7-9-19)10-14-11-17-12-18-14/h2-5,11-13H,6-10H2,1H3,(H,17,18)	Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321816 (4-((1H-Imidazol-4-yl)methyl)-1-(4-methoxyphenyl)pi...) Show SMILES COc1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C16H21N3O/c1-20-16-4-2-15(3-5-16)19-8-6-13(7-9-19)10-14-11-17-12-18-14/h2-5,11-13H,6-10H2,1H3,(H,17,18)	Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.60	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Agonist activity at human recombinant histamine H3 receptor expressed in CHO-K1 cells assessed as [35S]GTPgammaS binding after 1 hr by liquid scintil...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair