BDBM50321819 1-((1H-Imidazol-4-yl)methyl)-4-(4-tert-butylphenyl)-piperazine::CHEMBL1173808

SMILES: CC(C)(C)c1ccc(cc1)N1CCN(Cc2cnc[nH]2)CC1

InChI Key: InChIKey=WKOBKDIXZOEFOJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321819   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321819 (1-((1H-Imidazol-4-yl)methyl)-4-(4-tert-butylphenyl...) Show SMILES CC(C)(C)c1ccc(cc1)N1CCN(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C18H26N4/c1-18(2,3)15-4-6-17(7-5-15)22-10-8-21(9-11-22)13-16-12-19-14-20-16/h4-7,12,14H,8-11,13H2,1-3H3,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair