BDBM50321822 4-((1H-Imidazol-4-yl)methyl)-1-(4-nitrophenyl)piperidine::CHEMBL1172753

SMILES: [O-][N+](=O)c1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1

InChI Key: InChIKey=UWQJLRSDWKXACT-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321822 (4-((1H-Imidazol-4-yl)methyl)-1-(4-nitrophenyl)pipe...) Show SMILES [O-][N+](=O)c1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C15H18N4O2/c20-19(21)15-3-1-14(2-4-15)18-7-5-12(6-8-18)9-13-10-16-11-17-13/h1-4,10-12H,5-9H2,(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321822 (4-((1H-Imidazol-4-yl)methyl)-1-(4-nitrophenyl)pipe...) Show SMILES [O-][N+](=O)c1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C15H18N4O2/c20-19(21)15-3-1-14(2-4-15)18-7-5-12(6-8-18)9-13-10-16-11-17-13/h1-4,10-12H,5-9H2,(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.80	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Agonist activity at human recombinant histamine H3 receptor expressed in CHO-K1 cells assessed as [35S]GTPgammaS binding after 1 hr by liquid scintil...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair