BDBM50321845 8-[5-(4-Chlorophenyl)oxazol-2-ylamino]-1,2,3,4-tetrahydronaphthalen-2-ol::CHEMBL1172740
SMILES: OC1CCc2cccc(Nc3ncc(o3)-c3ccc(Cl)cc3)c2C1
InChI Key: InChIKey=TYICIIYZUHYVCH-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50321845 (8-[5-(4-Chlorophenyl)oxazol-2-ylamino]-1,2,3,4-tet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca... | Bioorg Med Chem 18: 4821-9 (2011) Article DOI: 10.1016/j.bmc.2010.04.099 BindingDB Entry DOI: 10.7270/Q27H1KJJ | |||||||||||
More data for this Ligand-Target Pair |