BDBM50321856 4-{2-[7-Hydroxy-5,6,7,8-tetrahydronaphthalen-1-ylamino]-5-[4-(trifluoromethyl)-phenyl]oxazol-4-yl}benzonitrile::CHEMBL1173690
SMILES: OC1CCc2cccc(Nc3nc(c(o3)-c3ccc(cc3)C(F)(F)F)-c3ccc(cc3)C#N)c2C1
InChI Key: InChIKey=KVUKMCYRADIGGS-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50321856 (4-{2-[7-Hydroxy-5,6,7,8-tetrahydronaphthalen-1-yla...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca... | Bioorg Med Chem 18: 4821-9 (2011) Article DOI: 10.1016/j.bmc.2010.04.099 BindingDB Entry DOI: 10.7270/Q27H1KJJ | |||||||||||
More data for this Ligand-Target Pair |