BDBM50321896 (Z)-2,4-Dimethyl-5-[2-oxo-6-(3-p-tolylureido)-1,2-dihydroindol-3-ylidene-methyl]-1H-pyrrole-3-carboxylic acid::CHEMBL1172420

SMILES: Cc1[nH]c(\C=C2/C(=O)Nc3cc(NC(=O)Nc4ccc(C)cc4)ccc23)c(C)c1C(O)=O

InChI Key: InChIKey=MAQBPYJYNOISMO-WQRHYEAKSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50321896 ((Z)-2,4-Dimethyl-5-[2-oxo-6-(3-p-tolylureido)-1,2-...) Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3cc(NC(=O)Nc4ccc(C)cc4)ccc23)c(C)c1C(O)=O Show InChI InChI=1S/C24H22N4O4/c1-12-4-6-15(7-5-12)26-24(32)27-16-8-9-17-18(22(29)28-20(17)10-16)11-19-13(2)21(23(30)31)14(3)25-19/h4-11,25H,1-3H3,(H,28,29)(H,30,31)(H2,26,27,32)/b18-11-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of VEGFR3				Bioorg Med Chem 18: 4674-86 (2011) Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50321896 ((Z)-2,4-Dimethyl-5-[2-oxo-6-(3-p-tolylureido)-1,2-...) Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3cc(NC(=O)Nc4ccc(C)cc4)ccc23)c(C)c1C(O)=O Show InChI InChI=1S/C24H22N4O4/c1-12-4-6-15(7-5-12)26-24(32)27-16-8-9-17-18(22(29)28-20(17)10-16)11-19-13(2)21(23(30)31)14(3)25-19/h4-11,25H,1-3H3,(H,28,29)(H,30,31)(H2,26,27,32)/b18-11-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem 18: 4674-86 (2011) Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50321896 ((Z)-2,4-Dimethyl-5-[2-oxo-6-(3-p-tolylureido)-1,2-...) Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3cc(NC(=O)Nc4ccc(C)cc4)ccc23)c(C)c1C(O)=O Show InChI InChI=1S/C24H22N4O4/c1-12-4-6-15(7-5-12)26-24(32)27-16-8-9-17-18(22(29)28-20(17)10-16)11-19-13(2)21(23(30)31)14(3)25-19/h4-11,25H,1-3H3,(H,28,29)(H,30,31)(H2,26,27,32)/b18-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of FLT3				Bioorg Med Chem 18: 4674-86 (2011) Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS
					More data for this Ligand-Target Pair