BDBM50321901 (Z)-4-Methyl-5-[2-oxo-6-(3-phenylureido)-1,2-dihydroindol-3-ylidenemethyl]-1H-pyrrole-2-carboxylic acid::CHEMBL1173542

SMILES: Cc1cc([nH]c1\C=C1/C(=O)Nc2cc(NC(=O)Nc3ccccc3)ccc12)C(O)=O

InChI Key: InChIKey=DEYLMMAOKCQOMO-WJDWOHSUSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50321901 ((Z)-4-Methyl-5-[2-oxo-6-(3-phenylureido)-1,2-dihyd...) Show SMILES Cc1cc([nH]c1\C=C1/C(=O)Nc2cc(NC(=O)Nc3ccccc3)ccc12)C(O)=O Show InChI InChI=1S/C22H18N4O4/c1-12-9-19(21(28)29)25-17(12)11-16-15-8-7-14(10-18(15)26-20(16)27)24-22(30)23-13-5-3-2-4-6-13/h2-11,25H,1H3,(H,26,27)(H,28,29)(H2,23,24,30)/b16-11-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of VEGFR3				Bioorg Med Chem 18: 4674-86 (2011) Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50321901 ((Z)-4-Methyl-5-[2-oxo-6-(3-phenylureido)-1,2-dihyd...) Show SMILES Cc1cc([nH]c1\C=C1/C(=O)Nc2cc(NC(=O)Nc3ccccc3)ccc12)C(O)=O Show InChI InChI=1S/C22H18N4O4/c1-12-9-19(21(28)29)25-17(12)11-16-15-8-7-14(10-18(15)26-20(16)27)24-22(30)23-13-5-3-2-4-6-13/h2-11,25H,1H3,(H,26,27)(H,28,29)(H2,23,24,30)/b16-11-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem 18: 4674-86 (2011) Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50321901 ((Z)-4-Methyl-5-[2-oxo-6-(3-phenylureido)-1,2-dihyd...) Show SMILES Cc1cc([nH]c1\C=C1/C(=O)Nc2cc(NC(=O)Nc3ccccc3)ccc12)C(O)=O Show InChI InChI=1S/C22H18N4O4/c1-12-9-19(21(28)29)25-17(12)11-16-15-8-7-14(10-18(15)26-20(16)27)24-22(30)23-13-5-3-2-4-6-13/h2-11,25H,1H3,(H,26,27)(H,28,29)(H2,23,24,30)/b16-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of FLT3				Bioorg Med Chem 18: 4674-86 (2011) Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS
					More data for this Ligand-Target Pair