Found 3 hits for monomerid = 50321902 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human)) | BDBM50321902
((Z)-5-{6[3-(4-Chlorophenyl)-ureido]-2-oxo-1,2-dihy...)Show SMILES Cc1cc([nH]c1\C=C1/C(=O)Nc2cc(NC(=O)Nc3ccc(Cl)cc3)ccc12)C(O)=O Show InChI InChI=1S/C22H17ClN4O4/c1-11-8-19(21(29)30)26-17(11)10-16-15-7-6-14(9-18(15)27-20(16)28)25-22(31)24-13-4-2-12(23)3-5-13/h2-10,26H,1H3,(H,27,28)(H,29,30)(H2,24,25,31)/b16-10- | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of VEGFR3 |
Bioorg Med Chem 18: 4674-86 (2011)
Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50321902
((Z)-5-{6[3-(4-Chlorophenyl)-ureido]-2-oxo-1,2-dihy...)Show SMILES Cc1cc([nH]c1\C=C1/C(=O)Nc2cc(NC(=O)Nc3ccc(Cl)cc3)ccc12)C(O)=O Show InChI InChI=1S/C22H17ClN4O4/c1-11-8-19(21(29)30)26-17(11)10-16-15-7-6-14(9-18(15)27-20(16)28)25-22(31)24-13-4-2-12(23)3-5-13/h2-10,26H,1H3,(H,27,28)(H,29,30)(H2,24,25,31)/b16-10- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of KDR |
Bioorg Med Chem 18: 4674-86 (2011)
Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50321902
((Z)-5-{6[3-(4-Chlorophenyl)-ureido]-2-oxo-1,2-dihy...)Show SMILES Cc1cc([nH]c1\C=C1/C(=O)Nc2cc(NC(=O)Nc3ccc(Cl)cc3)ccc12)C(O)=O Show InChI InChI=1S/C22H17ClN4O4/c1-11-8-19(21(29)30)26-17(11)10-16-15-7-6-14(9-18(15)27-20(16)28)25-22(31)24-13-4-2-12(23)3-5-13/h2-10,26H,1H3,(H,27,28)(H,29,30)(H2,24,25,31)/b16-10- | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of FLT3 |
Bioorg Med Chem 18: 4674-86 (2011)
Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS |
More data for this Ligand-Target Pair | |