BDBM50321904 (Z)-5-{6-[3-(4-Methoxyphenyl)-urido]-2-oxo-1,2-dihydro-indol-3-ylidene-methyl}thiophen-2-carboxylic acid::CHEMBL1172410

SMILES: COc1ccc(NC(=O)Nc2ccc3\C(=C\c4[nH]ccc4-c4ccc(s4)C(O)=O)C(=O)Nc3c2)cc1

InChI Key: InChIKey=UPCRMUKTOSKWMG-UYRXBGFRSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50321904 ((Z)-5-{6-[3-(4-Methoxyphenyl)-urido]-2-oxo-1,2-dih...) Show SMILES COc1ccc(NC(=O)Nc2ccc3\C(=C\c4[nH]ccc4-c4ccc(s4)C(O)=O)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C26H20N4O5S/c1-35-16-5-2-14(3-6-16)28-26(34)29-15-4-7-17-19(24(31)30-21(17)12-15)13-20-18(10-11-27-20)22-8-9-23(36-22)25(32)33/h2-13,27H,1H3,(H,30,31)(H,32,33)(H2,28,29,34)/b19-13-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of FLT3				Bioorg Med Chem 18: 4674-86 (2011) Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS
					More data for this Ligand-Target Pair
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50321904 ((Z)-5-{6-[3-(4-Methoxyphenyl)-urido]-2-oxo-1,2-dih...) Show SMILES COc1ccc(NC(=O)Nc2ccc3\C(=C\c4[nH]ccc4-c4ccc(s4)C(O)=O)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C26H20N4O5S/c1-35-16-5-2-14(3-6-16)28-26(34)29-15-4-7-17-19(24(31)30-21(17)12-15)13-20-18(10-11-27-20)22-8-9-23(36-22)25(32)33/h2-13,27H,1H3,(H,30,31)(H,32,33)(H2,28,29,34)/b19-13-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of VEGFR3				Bioorg Med Chem 18: 4674-86 (2011) Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS
					More data for this Ligand-Target Pair