BDBM50321977 CHEMBL1173247::N-(3-Methoxyphenyl)-2-(4-(2-hydroxyethyl)piperazin-1-yl)-9H-purin-6-amine

SMILES: COc1cccc(Nc2nc(nc3nc[nH]c23)N2CCN(CCO)CC2)c1

InChI Key: InChIKey=CPZZPNFLVVKVQF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50321977 (CHEMBL1173247 | N-(3-Methoxyphenyl)-2-(4-(2-hydrox...) Show SMILES COc1cccc(Nc2nc(nc3nc[nH]c23)N2CCN(CCO)CC2)c1 Show InChI InChI=1S/C18H23N7O2/c1-27-14-4-2-3-13(11-14)21-17-15-16(20-12-19-15)22-18(23-17)25-7-5-24(6-8-25)9-10-26/h2-4,11-12,26H,5-10H2,1H3,(H2,19,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition cSRC				Bioorg Med Chem 18: 4615-24 (2011) Article DOI: 10.1016/j.bmc.2010.05.032 BindingDB Entry DOI: 10.7270/Q26H4JCQ
					More data for this Ligand-Target Pair