BDBM50321998 3-(3,4-Dichlorophenyl)-5-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide::CHEMBL1173667

SMILES: NC(=S)N1N=C(CC1c1ccc(O)cc1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=QNLDNZHJFQMGHT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50321998 (3-(3,4-Dichlorophenyl)-5-(4-hydroxyphenyl)-4,5-dih...) Show SMILES NC(=S)N1N=C(CC1c1ccc(O)cc1)c1ccc(Cl)c(Cl)c1 |c:4| Show InChI InChI=1S/C16H13Cl2N3OS/c17-12-6-3-10(7-13(12)18)14-8-15(21(20-14)16(19)23)9-1-4-11(22)5-2-9/h1-7,15,22H,8H2,(H2,19,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of histidine-tagged recombinant EGFR autophosphorylation expressed in Sf9 cells by solid-phase ELISA				Bioorg Med Chem 18: 4606-14 (2011) Article DOI: 10.1016/j.bmc.2010.05.034 BindingDB Entry DOI: 10.7270/Q22R3SMJ
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50321998 (3-(3,4-Dichlorophenyl)-5-(4-hydroxyphenyl)-4,5-dih...) Show SMILES NC(=S)N1N=C(CC1c1ccc(O)cc1)c1ccc(Cl)c(Cl)c1 |c:4| Show InChI InChI=1S/C16H13Cl2N3OS/c17-12-6-3-10(7-13(12)18)14-8-15(21(20-14)16(19)23)9-1-4-11(22)5-2-9/h1-7,15,22H,8H2,(H2,19,23)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of human recombinant HER-2 cytoplasmic domain (676 to 1245) autophosphorylation after 1 hr				Bioorg Med Chem 21: 1050-63 (2013) Article DOI: 10.1016/j.bmc.2013.01.013 BindingDB Entry DOI: 10.7270/Q27S7Q3D
					More data for this Ligand-Target Pair