BDBM50322037 CHEMBL1173126::Ethyl(2S,6S)-2,6-dimethyl-4-({[7-(methylcarbamoyl)-8H-indeno[1,2-d][1,3]thiazol-4-yl]oxy}methyl)-7-oxo-8-oxa-3,5-diaza-4-phosphadecan-1-oate 4-oxide

SMILES: CCOC(=O)[C@H](C)NP(=O)(COc1ccc(C(=O)NC)c2Cc3scnc3-c12)N[C@@H](C)C(=O)OCC

InChI Key: InChIKey=QGONEYUXXNZCRN-KBPBESRZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322037   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase 1 (FBPase) (Homo sapiens (Human))	BDBM50322037 (CHEMBL1173126 | Ethyl(2S,6S)-2,6-dimethyl-4-({[7-(...) Show SMILES CCOC(=O)[C@H](C)NP(=O)(COc1ccc(C(=O)NC)c2Cc3scnc3-c12)N[C@@H](C)C(=O)OCC |r| Show InChI InChI=1S/C23H31N4O7PS/c1-6-32-22(29)13(3)26-35(31,27-14(4)23(30)33-7-2)12-34-17-9-8-15(21(28)24-5)16-10-18-20(19(16)17)25-11-36-18/h8-9,11,13-14H,6-7,10,12H2,1-5H3,(H,24,28)(H2,26,27,31)/t13-,14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FBase				Bioorg Med Chem 18: 5346-51 (2010) Article DOI: 10.1016/j.bmc.2010.05.041 BindingDB Entry DOI: 10.7270/Q2TB17V0
					More data for this Ligand-Target Pair