BDBM50322046 3,4,5-Trimethoxy-4'-amino-trans-stilbene::4-[2-(3,4,5-Trimethoxy-phenyl)-vinyl]-phenylamine::CHEMBL87477
SMILES: COc1cc(\C=C\c2ccc(N)cc2)cc(OC)c1OC
InChI Key: InChIKey=MWXBWYJFAGYFKS-SNAWJCMRSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 19A1 (Homo sapiens (Human)) | BDBM50322046 (3,4,5-Trimethoxy-4'-amino-trans-stilbene | 4-[2-(3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human aromatase preincubated with NADP+ for 10 mins before substrate addition measured after 30 mins | Bioorg Med Chem 18: 5352-66 (2010) Article DOI: 10.1016/j.bmc.2010.05.042 BindingDB Entry DOI: 10.7270/Q2PK0H4P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosyldihydronicotinamide dehydrogenase [quinone] (Homo sapiens (Human)) | BDBM50322046 (3,4,5-Trimethoxy-4'-amino-trans-stilbene | 4-[2-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) by UV-vis microplate reader analysis | Bioorg Med Chem 18: 5352-66 (2010) Article DOI: 10.1016/j.bmc.2010.05.042 BindingDB Entry DOI: 10.7270/Q2PK0H4P | |||||||||||
More data for this Ligand-Target Pair |