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BDBM50322048 2,4-Dimethoxy-3'-amino-trans-stilbene::CHEMBL1173641

SMILES: COc1ccc(\C=C\c2cccc(N)c2)c(OC)c1

InChI Key: InChIKey=YTHARJUESQVNDD-VOTSOKGWSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322048   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Homo sapiens (Human))
BDBM50322048
PNG
(2,4-Dimethoxy-3'-amino-trans-stilbene | CHEMBL1173...)
Show SMILES COc1ccc(\C=C\c2cccc(N)c2)c(OC)c1
Show InChI InChI=1S/C16H17NO2/c1-18-15-9-8-13(16(11-15)19-2)7-6-12-4-3-5-14(17)10-12/h3-11H,17H2,1-2H3/b7-6+
PDB
MMDB

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PC cid
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Article
PubMed
n/an/a 1.11E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of human aromatase preincubated with NADP+ for 10 mins before substrate addition measured after 30 mins


Bioorg Med Chem 18: 5352-66 (2010)


Article DOI: 10.1016/j.bmc.2010.05.042
BindingDB Entry DOI: 10.7270/Q2PK0H4P
More data for this
Ligand-Target Pair