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BDBM50322052 3,4,5-Trimethoxy-3'-amino-trans-stilbene::CHEMBL1173065

SMILES: COc1cc(\C=C\c2cccc(N)c2)cc(OC)c1OC

InChI Key: InChIKey=KHIQMXWOBUJQMV-BQYQJAHWSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322052   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Homo sapiens (Human))
BDBM50322052
PNG
(3,4,5-Trimethoxy-3'-amino-trans-stilbene | CHEMBL1...)
Show SMILES COc1cc(\C=C\c2cccc(N)c2)cc(OC)c1OC
Show InChI InChI=1S/C17H19NO3/c1-19-15-10-13(11-16(20-2)17(15)21-3)8-7-12-5-4-6-14(18)9-12/h4-11H,18H2,1-3H3/b8-7+
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 1.64E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of human aromatase preincubated with NADP+ for 10 mins before substrate addition measured after 30 mins


Bioorg Med Chem 18: 5352-66 (2010)


Article DOI: 10.1016/j.bmc.2010.05.042
BindingDB Entry DOI: 10.7270/Q2PK0H4P
More data for this
Ligand-Target Pair