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BDBM50322053 2,3,4-Trimethoxy-4'-amino-trans-stilbene::CHEMBL1173067

SMILES: COc1ccc(\C=C\c2ccc(N)cc2)c(OC)c1OC

InChI Key: InChIKey=YLCPSZLMRABQDV-QPJJXVBHSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322053   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Homo sapiens (Human))
BDBM50322053
PNG
(2,3,4-Trimethoxy-4'-amino-trans-stilbene | CHEMBL1...)
Show SMILES COc1ccc(\C=C\c2ccc(N)cc2)c(OC)c1OC
Show InChI InChI=1S/C17H19NO3/c1-19-15-11-8-13(16(20-2)17(15)21-3)7-4-12-5-9-14(18)10-6-12/h4-11H,18H2,1-3H3/b7-4+
PDB
MMDB

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PC cid
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Article
PubMed
n/an/a 3.57E+3n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of human aromatase preincubated with NADP+ for 10 mins before substrate addition measured after 30 mins


Bioorg Med Chem 18: 5352-66 (2010)


Article DOI: 10.1016/j.bmc.2010.05.042
BindingDB Entry DOI: 10.7270/Q2PK0H4P
More data for this
Ligand-Target Pair