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BDBM50322056 (E)-4-(2-(Benzo[d][1,3]dioxol-5-yl)vinyl)benzenamine::CHEMBL1173130

SMILES: Nc1ccc(\C=C\c2ccc3OCOc3c2)cc1

InChI Key: InChIKey=DDMGRJBNVVXAAX-OWOJBTEDSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322056   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Homo sapiens (Human))
BDBM50322056
PNG
((E)-4-(2-(Benzo[d][1,3]dioxol-5-yl)vinyl)benzenami...)
Show SMILES Nc1ccc(\C=C\c2ccc3OCOc3c2)cc1
Show InChI InChI=1S/C15H13NO2/c16-13-6-3-11(4-7-13)1-2-12-5-8-14-15(9-12)18-10-17-14/h1-9H,10,16H2/b2-1+
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.49E+3n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of human aromatase preincubated with NADP+ for 10 mins before substrate addition measured after 30 mins


Bioorg Med Chem 18: 5352-66 (2010)


Article DOI: 10.1016/j.bmc.2010.05.042
BindingDB Entry DOI: 10.7270/Q2PK0H4P
More data for this
Ligand-Target Pair