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BDBM50322064 3,5-Diamino-4'-amino-trans-stilbene::CHEMBL1171091

SMILES: Nc1ccc(\C=C\c2cc(N)cc(N)c2)cc1

InChI Key: InChIKey=QRFAISVLMWANDO-OWOJBTEDSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322064   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Homo sapiens (Human))
BDBM50322064
PNG
(3,5-Diamino-4'-amino-trans-stilbene | CHEMBL117109...)
Show SMILES Nc1ccc(\C=C\c2cc(N)cc(N)c2)cc1
Show InChI InChI=1S/C14H15N3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9H,15-17H2/b2-1+
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.51E+3n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of human aromatase preincubated with NADP+ for 10 mins before substrate addition measured after 30 mins


Bioorg Med Chem 18: 5352-66 (2010)


Article DOI: 10.1016/j.bmc.2010.05.042
BindingDB Entry DOI: 10.7270/Q2PK0H4P
More data for this
Ligand-Target Pair