BDBM50322732 2-(5-methylisoxazol-3-ylamino)-2-oxoethyl 2-(furan-2-carboxamido)-3-phenylpropanoate::CHEMBL1172020::cid_3000182

SMILES: Cc1cc(NC(=O)COC(=O)C(Cc2ccccc2)NC(=O)c2ccco2)no1

InChI Key: InChIKey=ZYYMBBMNVVYCEY-UHFFFAOYSA-N

Data: 2 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50322732   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 11 (Homo sapiens (Human))	BDBM50322732 (2-(5-methylisoxazol-3-ylamino)-2-oxoethyl 2-(furan...) Show SMILES Cc1cc(NC(=O)COC(=O)C(Cc2ccccc2)NC(=O)c2ccco2)no1 Show InChI InChI=1S/C20H19N3O6/c1-13-10-17(23-29-13)22-18(24)12-28-20(26)15(11-14-6-3-2-4-7-14)21-19(25)16-8-5-9-27-16/h2-10,15H,11-12H2,1H3,(H,21,25)(H,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>3.50E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q24J0CKJ
					More data for this Ligand-Target Pair
Tropomyosin alpha-1 chain (Sus scrofa)	BDBM50322732 (2-(5-methylisoxazol-3-ylamino)-2-oxoethyl 2-(furan...) Show SMILES Cc1cc(NC(=O)COC(=O)C(Cc2ccccc2)NC(=O)c2ccco2)no1 Show InChI InChI=1S/C20H19N3O6/c1-13-10-17(23-29-13)22-18(24)12-28-20(26)15(11-14-6-3-2-4-7-14)21-19(25)16-8-5-9-27-16/h2-10,15H,11-12H2,1H3,(H,21,25)(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>7.15E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q21N7ZKB
					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50322732 (2-(5-methylisoxazol-3-ylamino)-2-oxoethyl 2-(furan...) Show SMILES Cc1cc(NC(=O)COC(=O)C(Cc2ccccc2)NC(=O)c2ccco2)no1 Show InChI InChI=1S/C20H19N3O6/c1-13-10-17(23-29-13)22-18(24)12-28-20(26)15(11-14-6-3-2-4-7-14)21-19(25)16-8-5-9-27-16/h2-10,15H,11-12H2,1H3,(H,21,25)(H,22,23,24)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzain assessed as Z-Phe-Arg-aminomethylcoumarin cleavage				J Med Chem 53: 4891-905 (2010) Article DOI: 10.1021/jm100488w BindingDB Entry DOI: 10.7270/Q2BG2P68
					More data for this Ligand-Target Pair
Galanin receptor type 3 (Homo sapiens (Human))	BDBM50322732 (2-(5-methylisoxazol-3-ylamino)-2-oxoethyl 2-(furan...) Show SMILES Cc1cc(NC(=O)COC(=O)C(Cc2ccccc2)NC(=O)c2ccco2)no1 Show InChI InChI=1S/C20H19N3O6/c1-13-10-17(23-29-13)22-18(24)12-28-20(26)15(11-14-6-3-2-4-7-14)21-19(25)16-8-5-9-27-16/h2-10,15H,11-12H2,1H3,(H,21,25)(H,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>2.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q270802Q
					More data for this Ligand-Target Pair
Corticotropin-releasing factor-binding protein (Homo sapiens (Human))	BDBM50322732 (2-(5-methylisoxazol-3-ylamino)-2-oxoethyl 2-(furan...) Show SMILES Cc1cc(NC(=O)COC(=O)C(Cc2ccccc2)NC(=O)c2ccco2)no1 Show InChI InChI=1S/C20H19N3O6/c1-13-10-17(23-29-13)22-18(24)12-28-20(26)15(11-14-6-3-2-4-7-14)21-19(25)16-8-5-9-27-16/h2-10,15H,11-12H2,1H3,(H,21,25)(H,22,23,24)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	4.49E+3	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2VX0F3D
					More data for this Ligand-Target Pair