BDBM50322813 4-[2-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-ylamino)ethyl]phenol::CHEMBL1173116

SMILES: Oc1ccc(CCNc2ncnc3oc(c(-c4ccccc4)c23)-c2ccccc2)cc1

InChI Key: InChIKey=PSWCNYTWNWKUHT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322813   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50322813 (4-[2-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-ylamino)e...) Show SMILES Oc1ccc(CCNc2ncnc3oc(c(-c4ccccc4)c23)-c2ccccc2)cc1 Show InChI InChI=1S/C26H21N3O2/c30-21-13-11-18(12-14-21)15-16-27-25-23-22(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)31-26(23)29-17-28-25/h1-14,17,30H,15-16H2,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair