BDBM50322815 (4-Aminobenzyl)-(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amine::CHEMBL1172780

SMILES: Nc1ccc(CNc2ncnc3oc(c(-c4ccccc4)c23)-c2ccccc2)cc1

InChI Key: InChIKey=YEQBDZQJZDWCJS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50322815 ((4-Aminobenzyl)-(5,6-diphenylfuro[2,3-d]pyrimidin-...) Show SMILES Nc1ccc(CNc2ncnc3oc(c(-c4ccccc4)c23)-c2ccccc2)cc1 Show InChI InChI=1S/C25H20N4O/c26-20-13-11-17(12-14-20)15-27-24-22-21(18-7-3-1-4-8-18)23(19-9-5-2-6-10-19)30-25(22)29-16-28-24/h1-14,16H,15,26H2,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	945	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair