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SMILES: O=C(Nc1ncnc2nc([nH]c12)-c1cccc(c1)C#N)C1CC1

InChI Key: InChIKey=PNNMFSLFIVLTJQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322827   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))		BDBM50322827
PNG
(CHEMBL1210405 | N-(8-(3-cyanophenyl)-9H-purin-6-yl...)
Show SMILES O=C(Nc1ncnc2nc([nH]c12)-c1cccc(c1)C#N)C1CC1
Show InChI InChI=1S/C16H12N6O/c17-7-9-2-1-3-11(6-9)13-20-12-14(21-13)18-8-19-15(12)22-16(23)10-4-5-10/h1-3,6,8,10H,4-5H2,(H2,18,19,20,21,22,23)
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Article
PubMed
n/an/a 781n/an/an/an/an/an/a



Centre Universitaire

Curated by ChEMBL


Assay Description
Inhibition of human GSK3beta

Eur J Med Chem 45: 3389-93 (2010)


Article DOI: 10.1016/j.ejmech.2010.04.026
BindingDB Entry DOI: 10.7270/Q2TH8MWC
More data for this
Ligand-Target Pair