BDBM50322856 (R)-3-phenyl-N-((R)-6-(1-(piperidin-1-ylmethyl)cyclopropyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide::CHEMBL1210742

SMILES: FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C1(CN2CCCCC2)CC1)c1ccccc1

InChI Key: InChIKey=XVKFTKTYQSDOGT-ROJLCIKYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322856   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50322856 ((R)-3-phenyl-N-((R)-6-(1-(piperidin-1-ylmethyl)cyc...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C1(CN2CCCCC2)CC1)c1ccccc1 |r| Show InChI InChI=1S/C35H40F3N3O3S/c36-35(37,38)28-12-8-13-29(22-28)45(43,44)40-32(25-9-3-1-4-10-25)23-33(42)39-31-14-7-11-26-21-27(15-16-30(26)31)34(17-18-34)24-41-19-5-2-6-20-41/h1,3-4,8-10,12-13,15-16,21-22,31-32,40H,2,5-7,11,14,17-20,23-24H2,(H,39,42)/t31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50322856 ((R)-3-phenyl-N-((R)-6-(1-(piperidin-1-ylmethyl)cyc...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C1(CN2CCCCC2)CC1)c1ccccc1 |r| Show InChI InChI=1S/C35H40F3N3O3S/c36-35(37,38)28-12-8-13-29(22-28)45(43,44)40-32(25-9-3-1-4-10-25)23-33(42)39-31-14-7-11-26-21-27(15-16-30(26)31)34(17-18-34)24-41-19-5-2-6-20-41/h1,3-4,8-10,12-13,15-16,21-22,31-32,40H,2,5-7,11,14,17-20,23-24H2,(H,39,42)/t31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair