BDBM50322857 (R)-3-phenyl-N-((R)-6-(3-(piperidin-1-yl)prop-1-en-2-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide::CHEMBL1210743

SMILES: FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCCCC1)c1ccccc1

InChI Key: InChIKey=MYWRAUVBMJOKMA-ROJLCIKYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322857 ((R)-3-phenyl-N-((R)-6-(3-(piperidin-1-yl)prop-1-en...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCCCC1)c1ccccc1 |r| Show InChI InChI=1S/C34H38F3N3O3S/c1-24(23-40-18-6-3-7-19-40)26-16-17-30-27(20-26)12-8-15-31(30)38-33(41)22-32(25-10-4-2-5-11-25)39-44(42,43)29-14-9-13-28(21-29)34(35,36)37/h2,4-5,9-11,13-14,16-17,20-21,31-32,39H,1,3,6-8,12,15,18-19,22-23H2,(H,38,41)/t31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322857 ((R)-3-phenyl-N-((R)-6-(3-(piperidin-1-yl)prop-1-en...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCCCC1)c1ccccc1 |r| Show InChI InChI=1S/C34H38F3N3O3S/c1-24(23-40-18-6-3-7-19-40)26-16-17-30-27(20-26)12-8-15-31(30)38-33(41)22-32(25-10-4-2-5-11-25)39-44(42,43)29-14-9-13-28(21-29)34(35,36)37/h2,4-5,9-11,13-14,16-17,20-21,31-32,39H,1,3,6-8,12,15,18-19,22-23H2,(H,38,41)/t31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair