BDBM50322860 (R)-N-((R)-6-(3-((R)-3-hydroxypyrrolidin-1-yl)prop-1-en-2-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-phenyl-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide::CHEMBL1210746

SMILES: O[C@@H]1CCN(CC(=C)c2ccc3[C@@H](CCCc3c2)NC(=O)C[C@@H](NS(=O)(=O)c2cccc(c2)C(F)(F)F)c2ccccc2)C1

InChI Key: InChIKey=SUTWITAROAZMMF-VEIFUORISA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322860 ((R)-N-((R)-6-(3-((R)-3-hydroxypyrrolidin-1-yl)prop...) Show SMILES O[C@@H]1CCN(CC(=C)c2ccc3[C@@H](CCCc3c2)NC(=O)C[C@@H](NS(=O)(=O)c2cccc(c2)C(F)(F)F)c2ccccc2)C1 |r| Show InChI InChI=1S/C33H36F3N3O4S/c1-22(20-39-16-15-27(40)21-39)24-13-14-29-25(17-24)9-5-12-30(29)37-32(41)19-31(23-7-3-2-4-8-23)38-44(42,43)28-11-6-10-26(18-28)33(34,35)36/h2-4,6-8,10-11,13-14,17-18,27,30-31,38,40H,1,5,9,12,15-16,19-21H2,(H,37,41)/t27-,30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322860 ((R)-N-((R)-6-(3-((R)-3-hydroxypyrrolidin-1-yl)prop...) Show SMILES O[C@@H]1CCN(CC(=C)c2ccc3[C@@H](CCCc3c2)NC(=O)C[C@@H](NS(=O)(=O)c2cccc(c2)C(F)(F)F)c2ccccc2)C1 |r| Show InChI InChI=1S/C33H36F3N3O4S/c1-22(20-39-16-15-27(40)21-39)24-13-14-29-25(17-24)9-5-12-30(29)37-32(41)19-31(23-7-3-2-4-8-23)38-44(42,43)28-11-6-10-26(18-28)33(34,35)36/h2-4,6-8,10-11,13-14,17-18,27,30-31,38,40H,1,5,9,12,15-16,19-21H2,(H,37,41)/t27-,30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair