BDBM50322861 (R)-N-((R)-6-(3-(azetidin-1-yl)prop-1-en-2-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-phenyl-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide::CHEMBL1210747

SMILES: FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCC1)c1ccccc1

InChI Key: InChIKey=JFIIULISSXNFKU-LOYHVIPDSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322861 ((R)-N-((R)-6-(3-(azetidin-1-yl)prop-1-en-2-yl)-1,2...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCC1)c1ccccc1 |r| Show InChI InChI=1S/C32H34F3N3O3S/c1-22(21-38-16-7-17-38)24-14-15-28-25(18-24)10-5-13-29(28)36-31(39)20-30(23-8-3-2-4-9-23)37-42(40,41)27-12-6-11-26(19-27)32(33,34)35/h2-4,6,8-9,11-12,14-15,18-19,29-30,37H,1,5,7,10,13,16-17,20-21H2,(H,36,39)/t29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322861 ((R)-N-((R)-6-(3-(azetidin-1-yl)prop-1-en-2-yl)-1,2...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCC1)c1ccccc1 |r| Show InChI InChI=1S/C32H34F3N3O3S/c1-22(21-38-16-7-17-38)24-14-15-28-25(18-24)10-5-13-29(28)36-31(39)20-30(23-8-3-2-4-9-23)37-42(40,41)27-12-6-11-26(19-27)32(33,34)35/h2-4,6,8-9,11-12,14-15,18-19,29-30,37H,1,5,7,10,13,16-17,20-21H2,(H,36,39)/t29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	206	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair