BDBM50322866 (R)-N-((R)-6-(3-(tert-butylamino)prop-1-en-2-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-phenyl-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide::CHEMBL1210752

SMILES: CC(C)(C)NCC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1

InChI Key: InChIKey=LGKHZXIFKYWRMS-LOYHVIPDSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322866   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322866 ((R)-N-((R)-6-(3-(tert-butylamino)prop-1-en-2-yl)-1...) Show SMILES CC(C)(C)NCC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C33H38F3N3O3S/c1-22(21-37-32(2,3)4)24-16-17-28-25(18-24)12-8-15-29(28)38-31(40)20-30(23-10-6-5-7-11-23)39-43(41,42)27-14-9-13-26(19-27)33(34,35)36/h5-7,9-11,13-14,16-19,29-30,37,39H,1,8,12,15,20-21H2,2-4H3,(H,38,40)/t29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322866 ((R)-N-((R)-6-(3-(tert-butylamino)prop-1-en-2-yl)-1...) Show SMILES CC(C)(C)NCC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C33H38F3N3O3S/c1-22(21-37-32(2,3)4)24-16-17-28-25(18-24)12-8-15-29(28)38-31(40)20-30(23-10-6-5-7-11-23)39-43(41,42)27-14-9-13-26(19-27)33(34,35)36/h5-7,9-11,13-14,16-19,29-30,37,39H,1,8,12,15,20-21H2,2-4H3,(H,38,40)/t29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair