BDBM50322868 (R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-phenyl-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide::CHEMBL1210754

SMILES: FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CNC1CCC1)c1ccccc1

InChI Key: InChIKey=MNVHGPUKRNXZDQ-FIRIVFDPSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322868 ((R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CNC1CCC1)c1ccccc1 |r| Show InChI InChI=1S/C33H36F3N3O3S/c1-22(21-37-27-12-7-13-27)24-16-17-29-25(18-24)10-5-15-30(29)38-32(40)20-31(23-8-3-2-4-9-23)39-43(41,42)28-14-6-11-26(19-28)33(34,35)36/h2-4,6,8-9,11,14,16-19,27,30-31,37,39H,1,5,7,10,12-13,15,20-21H2,(H,38,40)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322868 ((R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CNC1CCC1)c1ccccc1 |r| Show InChI InChI=1S/C33H36F3N3O3S/c1-22(21-37-27-12-7-13-27)24-16-17-29-25(18-24)10-5-15-30(29)38-32(40)20-31(23-8-3-2-4-9-23)39-43(41,42)28-14-6-11-26(19-28)33(34,35)36/h2-4,6,8-9,11,14,16-19,27,30-31,37,39H,1,5,7,10,12-13,15,20-21H2,(H,38,40)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair