null

SMILES: Fc1cc(F)cc(NC(=O)N2CCC3(CC2)C(N(C3=O)c2cccc(c2)C#N)c2ccccn2)c1

InChI Key: InChIKey=HFAPBMCMVMGMST-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50322944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322944 (2-(3-cyanophenyl)-N-(3,5-difluorophenyl)-1-oxo-3-(...) Show SMILES Fc1cc(F)cc(NC(=O)N2CCC3(CC2)C(N(C3=O)c2cccc(c2)C#N)c2ccccn2)c1 Show InChI InChI=1S/C26H21F2N5O2/c27-18-13-19(28)15-20(14-18)31-25(35)32-10-7-26(8-11-32)23(22-6-1-2-9-30-22)33(24(26)34)21-5-3-4-17(12-21)16-29/h1-6,9,12-15,23H,7-8,10-11H2,(H,31,35)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assay				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322944 (2-(3-cyanophenyl)-N-(3,5-difluorophenyl)-1-oxo-3-(...) Show SMILES Fc1cc(F)cc(NC(=O)N2CCC3(CC2)C(N(C3=O)c2cccc(c2)C#N)c2ccccn2)c1 Show InChI InChI=1S/C26H21F2N5O2/c27-18-13-19(28)15-20(14-18)31-25(35)32-10-7-26(8-11-32)23(22-6-1-2-9-30-22)33(24(26)34)21-5-3-4-17(12-21)16-29/h1-6,9,12-15,23H,7-8,10-11H2,(H,31,35)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	247	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assay				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322944 (2-(3-cyanophenyl)-N-(3,5-difluorophenyl)-1-oxo-3-(...) Show SMILES Fc1cc(F)cc(NC(=O)N2CCC3(CC2)C(N(C3=O)c2cccc(c2)C#N)c2ccccn2)c1 Show InChI InChI=1S/C26H21F2N5O2/c27-18-13-19(28)15-20(14-18)31-25(35)32-10-7-26(8-11-32)23(22-6-1-2-9-30-22)33(24(26)34)21-5-3-4-17(12-21)16-29/h1-6,9,12-15,23H,7-8,10-11H2,(H,31,35)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	732	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assay				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322944 (2-(3-cyanophenyl)-N-(3,5-difluorophenyl)-1-oxo-3-(...) Show SMILES Fc1cc(F)cc(NC(=O)N2CCC3(CC2)C(N(C3=O)c2cccc(c2)C#N)c2ccccn2)c1 Show InChI InChI=1S/C26H21F2N5O2/c27-18-13-19(28)15-20(14-18)31-25(35)32-10-7-26(8-11-32)23(22-6-1-2-9-30-22)33(24(26)34)21-5-3-4-17(12-21)16-29/h1-6,9,12-15,23H,7-8,10-11H2,(H,31,35)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp method				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair