BDBM50322960 (2S,3S)-methyl 2-(1-(4-chlorophenyl)-2-(3-fluorophenyl)-2,7-diazaspiro[3.5]nonane-7-carboxamido)-3-methylpentanoate::CHEMBL1210266

SMILES: CC[C@H](C)[C@H](NC(=O)N1CCC2(CN(C2c2ccc(Cl)cc2)c2cccc(F)c2)CC1)C(=O)OC

InChI Key: InChIKey=ZLEWURJVFDNZRR-VHXBAKGZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322960 ((2S,3S)-methyl 2-(1-(4-chlorophenyl)-2-(3-fluoroph...) Show SMILES CC[C@H](C)[C@H](NC(=O)N1CCC2(CN(C2c2ccc(Cl)cc2)c2cccc(F)c2)CC1)C(=O)OC |r| Show InChI InChI=1S/C27H33ClFN3O3/c1-4-18(2)23(25(33)35-3)30-26(34)31-14-12-27(13-15-31)17-32(22-7-5-6-21(29)16-22)24(27)19-8-10-20(28)11-9-19/h5-11,16,18,23-24H,4,12-15,17H2,1-3H3,(H,30,34)/t18-,23-,24?/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assay				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322960 ((2S,3S)-methyl 2-(1-(4-chlorophenyl)-2-(3-fluoroph...) Show SMILES CC[C@H](C)[C@H](NC(=O)N1CCC2(CN(C2c2ccc(Cl)cc2)c2cccc(F)c2)CC1)C(=O)OC |r| Show InChI InChI=1S/C27H33ClFN3O3/c1-4-18(2)23(25(33)35-3)30-26(34)31-14-12-27(13-15-31)17-32(22-7-5-6-21(29)16-22)24(27)19-8-10-20(28)11-9-19/h5-11,16,18,23-24H,4,12-15,17H2,1-3H3,(H,30,34)/t18-,23-,24?/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assay				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair