null

SMILES: CC(C)N1CC2(CCN(CC2)C(=O)Nc2ccc(F)c(F)c2)C1c1ccc(Cl)cc1

InChI Key: InChIKey=IVIJESHEJVFCAI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322964 (1-(4-chlorophenyl)-N-(3,4-difluorophenyl)-2-isopro...) Show SMILES CC(C)N1CC2(CCN(CC2)C(=O)Nc2ccc(F)c(F)c2)C1c1ccc(Cl)cc1 Show InChI InChI=1S/C23H26ClF2N3O/c1-15(2)29-14-23(21(29)16-3-5-17(24)6-4-16)9-11-28(12-10-23)22(30)27-18-7-8-19(25)20(26)13-18/h3-8,13,15,21H,9-12,14H2,1-2H3,(H,27,30)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp method				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322964 (1-(4-chlorophenyl)-N-(3,4-difluorophenyl)-2-isopro...) Show SMILES CC(C)N1CC2(CCN(CC2)C(=O)Nc2ccc(F)c(F)c2)C1c1ccc(Cl)cc1 Show InChI InChI=1S/C23H26ClF2N3O/c1-15(2)29-14-23(21(29)16-3-5-17(24)6-4-16)9-11-28(12-10-23)22(30)27-18-7-8-19(25)20(26)13-18/h3-8,13,15,21H,9-12,14H2,1-2H3,(H,27,30)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	174	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assay				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair