null

SMILES: CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(N)nc2)cc(OCc2ccccc2)c1-c1ccc(F)cc1

InChI Key: InChIKey=VGTBCHGQRVWGCK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322978 (6-amino-N-(1-((2-(benzyloxy)-6-ethoxy-4'-fluorobip...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(N)nc2)cc(OCc2ccccc2)c1-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN4O3/c1-2-40-29-18-24(21-38-16-14-28(15-17-38)37-33(39)26-10-13-31(35)36-20-26)19-30(41-22-23-6-4-3-5-7-23)32(29)25-8-11-27(34)12-9-25/h3-13,18-20,28H,2,14-17,21-22H2,1H3,(H2,35,36)(H,37,39)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322978 (6-amino-N-(1-((2-(benzyloxy)-6-ethoxy-4'-fluorobip...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(N)nc2)cc(OCc2ccccc2)c1-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN4O3/c1-2-40-29-18-24(21-38-16-14-28(15-17-38)37-33(39)26-10-13-31(35)36-20-26)19-30(41-22-23-6-4-3-5-7-23)32(29)25-8-11-27(34)12-9-25/h3-13,18-20,28H,2,14-17,21-22H2,1H3,(H2,35,36)(H,37,39)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair