null

SMILES: C[C@@]12CN(C[C@@](C)(O1)c1c(O)n(c(O)c21)-c1ccc(C#N)c(c1)C(F)(F)F)S(=O)(=O)c1ccccn1

InChI Key: InChIKey=HNAMGZRGAAHAJP-SZPZYZBQSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50323034 (4-[(1S,2S,6R,7R)-1,7-Dimethyl-3,5-dioxo-9-(pyridin...) Show SMILES C[C@@]12CN(C[C@@](C)(O1)c1c(O)n(c(O)c21)-c1ccc(C#N)c(c1)C(F)(F)F)S(=O)(=O)c1ccccn1 |r| Show InChI InChI=1S/C23H19F3N4O5S/c1-21-11-29(36(33,34)16-5-3-4-8-28-16)12-22(2,35-21)18-17(21)19(31)30(20(18)32)14-7-6-13(10-27)15(9-14)23(24,25)26/h3-9,31-32H,11-12H2,1-2H3/t21-,22+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [3H]DHT from AR in human MDA-MB-453 cells				Bioorg Med Chem Lett 20: 4491-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.034 BindingDB Entry DOI: 10.7270/Q2MK6DVH
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50323034 (4-[(1S,2S,6R,7R)-1,7-Dimethyl-3,5-dioxo-9-(pyridin...) Show SMILES C[C@@]12CN(C[C@@](C)(O1)c1c(O)n(c(O)c21)-c1ccc(C#N)c(c1)C(F)(F)F)S(=O)(=O)c1ccccn1 |r| Show InChI InChI=1S/C23H19F3N4O5S/c1-21-11-29(36(33,34)16-5-3-4-8-28-16)12-22(2,35-21)18-17(21)19(31)30(20(18)32)14-7-6-13(10-27)15(9-14)23(24,25)26/h3-9,31-32H,11-12H2,1-2H3/t21-,22+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at human wild type AR expressed in human MDA-MB-435 cells by transactivation assay				Bioorg Med Chem Lett 20: 4491-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.034 BindingDB Entry DOI: 10.7270/Q2MK6DVH
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50323034 (4-[(1S,2S,6R,7R)-1,7-Dimethyl-3,5-dioxo-9-(pyridin...) Show SMILES C[C@@]12CN(C[C@@](C)(O1)c1c(O)n(c(O)c21)-c1ccc(C#N)c(c1)C(F)(F)F)S(=O)(=O)c1ccccn1 |r| Show InChI InChI=1S/C23H19F3N4O5S/c1-21-11-29(36(33,34)16-5-3-4-8-28-16)12-22(2,35-21)18-17(21)19(31)30(20(18)32)14-7-6-13(10-27)15(9-14)23(24,25)26/h3-9,31-32H,11-12H2,1-2H3/t21-,22+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at wild type human AR expressed in human LNCAP cells by transactivation assay				Bioorg Med Chem Lett 20: 4491-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.034 BindingDB Entry DOI: 10.7270/Q2MK6DVH
					More data for this Ligand-Target Pair