BDBM50323289 CHEMBL1209202::N-(3-chlorophenyl)-3-cyano-5-fluorobenzamide

SMILES: Fc1cc(cc(c1)C(=O)Nc1cccc(Cl)c1)C#N

InChI Key: InChIKey=FNDUFJARTKDXEF-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323289 (CHEMBL1209202 | N-(3-chlorophenyl)-3-cyano-5-fluor...) Show SMILES Fc1cc(cc(c1)C(=O)Nc1cccc(Cl)c1)C#N Show InChI InChI=1S/C14H8ClFN2O/c15-11-2-1-3-13(7-11)18-14(19)10-4-9(8-17)5-12(16)6-10/h1-7H,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	206	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Displacement of [3H]methoxy-PEPy from rat mGlu5 receptor expressed in HEK293A cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 4390-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.064 BindingDB Entry DOI: 10.7270/Q2V9888D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323289 (CHEMBL1209202 | N-(3-chlorophenyl)-3-cyano-5-fluor...) Show SMILES Fc1cc(cc(c1)C(=O)Nc1cccc(Cl)c1)C#N Show InChI InChI=1S/C14H8ClFN2O/c15-11-2-1-3-13(7-11)18-14(19)10-4-9(8-17)5-12(16)6-10/h1-7H,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at rat mGlu5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium mobilization				Bioorg Med Chem Lett 20: 4390-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.064 BindingDB Entry DOI: 10.7270/Q2V9888D
					More data for this Ligand-Target Pair