BindingDB logo
myBDB logout

BDBM50323391 5-isopropyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid::CHEMBL1208920

SMILES: CC(C)C1Cc2[nH]nc(C(O)=O)c2C1

InChI Key: InChIKey=GPBFYQJKFABUGU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323391   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hydroxycarboxylic acid receptor 2


(Homo sapiens (Human))
BDBM50323391
PNG
(5-isopropyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazol...)
Show SMILES CC(C)C1Cc2[nH]nc(C(O)=O)c2C1
Show InChI InChI=1S/C10H14N2O2/c1-5(2)6-3-7-8(4-6)11-12-9(7)10(13)14/h5-6H,3-4H2,1-2H3,(H,11,12)(H,13,14)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]nicotinic acid from human GPR10a receptor


Bioorg Med Chem Lett 20: 4472-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.041
More data for this
Ligand-Target Pair
Hydroxycarboxylic acid receptor 2


(Mus musculus)
BDBM50323391
PNG
(5-isopropyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazol...)
Show SMILES CC(C)C1Cc2[nH]nc(C(O)=O)c2C1
Show InChI InChI=1S/C10H14N2O2/c1-5(2)6-3-7-8(4-6)11-12-9(7)10(13)14/h5-6H,3-4H2,1-2H3,(H,11,12)(H,13,14)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 990n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]nicotinic acid from mouse GPR10a receptor


Bioorg Med Chem Lett 20: 4472-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.041
More data for this
Ligand-Target Pair