BDBM50323413 2-amino-N-(3-(3-tert-butyl-5-(3-phenylureido)-1H-pyrazol-1-yl)benzyl)acetamide::CHEMBL1209213
SMILES: CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(n1)-c1cccc(CNC(=O)CN)c1
InChI Key: InChIKey=PZUKQDSGLNPGCH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50323413 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50323413
(2-amino-N-(3-(3-tert-butyl-5-(3-phenylureido)-1H-p...)Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(n1)-c1cccc(CNC(=O)CN)c1 Show InChI InChI=1S/C23H28N6O2/c1-23(2,3)19-13-20(27-22(31)26-17-9-5-4-6-10-17)29(28-19)18-11-7-8-16(12-18)15-25-21(30)14-24/h4-13H,14-15,24H2,1-3H3,(H,25,30)(H2,26,27,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of active p38alpha |
Bioorg Med Chem Lett 20: 4885-91 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.073
BindingDB Entry DOI: 10.7270/Q2Z31ZT2 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50323413
(2-amino-N-(3-(3-tert-butyl-5-(3-phenylureido)-1H-p...)Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(n1)-c1cccc(CNC(=O)CN)c1 Show InChI InChI=1S/C23H28N6O2/c1-23(2,3)19-13-20(27-22(31)26-17-9-5-4-6-10-17)29(28-19)18-11-7-8-16(12-18)15-25-21(30)14-24/h4-13H,14-15,24H2,1-3H3,(H,25,30)(H2,26,27,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 176 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of unactive p38alpha |
Bioorg Med Chem Lett 20: 4885-91 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.073
BindingDB Entry DOI: 10.7270/Q2Z31ZT2 |
More data for this
Ligand-Target Pair | |
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